Clinical Pathways and Reference

Clinical Pathways and Reference products provide evidence-based, structured guidanceto manage specific diseases or conditions, with a focus on standardizing careand improving outcomes. While these products typically guide treatment after a diagnosis has been established, some may offer reference-based diagnostic toolsfor generating differential diagnoses. These tools allow physicians to input symptoms or clinical data and retrieve recommendations based on protocols or decision trees. However, unlike CDS, they are less integrated into real-time workflowsand require the clinician to actively interact with the platform to extract insights. Pathways products are typically integrated into EHRs to ensure clinicians follow the recommended steps and monitor adherence to treatment protocols.

Typical Capabilities of Clinical Pathways Products:

Evidence-Based Guidelines:Provide regularly updated protocols aligned with clinical research.Condition-Specific Pathways:Include predefined pathways for managing diseases such as cancer or chronic illnesses.Personalization:Tailor pathways based on individual patient demographics, comorbidities, and history.Diagnostic Reference Tools:Offer decision trees or protocol-based support for exploring differential diagnoses.EHR Integration:Ensure clinicians can access pathways directly within their workflow.Real-Time Decision Support:Provide actionable recommendations during patient encounters.Compliance Tracking:Generate reports to monitor adherence to guidelines and regulatory standards.

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Avo
Claimed

Avo

Company Info
Founded: 2020
Headcount: 11-50
Customers
Verified Customers: 17
Customers Served: Digital Health Provider, Hospital / Health System, Ambulatory Practice, Life Sciences
Product Overview
Security and Compliance Certifications: SOC 2 Type 2, HIPAA
AvoMD is a clinician support platform for transforming guidelines and protocols into actionable tools in the clinical workflow to enable organizations to standardize care with minimal technical effort. The product centralizes the latest clinical guidelines and transforms them into actionable tools within or outside of the EHR to help simplify tasks like documentation, ordering, and care plans.
Company Info
Founded: 2011
Headcount: 11-50
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: SOC 2 Type 2, HIPAA
AgileMD Clinical Pathways is a platform that helps healthcare providers design and implement evidence-based clinical pathways. It offers tools for creating, managing, and deploying guidelines directly into electronic health records (EHRs), ensuring that clinicians can access up-to-date clinical recommendations at the point of care. The platform also includes analytics to track and optimize care delivery based on real-time data.
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Atropos Health

Atropos Health

Company Info
Founded: 2020
Headcount: 11-50
Customers
Customers Served: Hospital / Health System, Life Sciences
Product Overview
Security and Compliance Certifications: HIPAA
Atropos Health provides evidence generation solutions that support clinical decision-making by utilizing real-world data (RWD). It offers tools for health systems, research institutions, and graduate medical education (GME) programs to derive insights from clinical and population health data. These insights can improve patient outcomes, enhance value-based care, and guide quality initiatives. The platform allows organizations to monitor interventions in real-time and leverage comparative effectiveness research to optimize clinical operations, care pathways, and drug formularies. Key capabilities include advanced cohorting, automated study designs, and real-time analytics to support personalized and evidence-based care.
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C8 Health

C8 Health

Company Info
Founded: 2021
Headcount: 1-10
Customers
Verified Customers: 1
Customers Served: Ambulatory Practice, Health Plan
Product Overview
C8 Health offers a clinical resource management platform that centralizes and disseminates clinical guidelines, knowledge bases, and protocols for hospitals. It provides features like AI-powered search, workflow integration, collaboration tools, and data analytics to help medical teams access, update, and share critical information efficiently. The platform aims to reduce variability in care by making best practices easily accessible across departments, supporting faster decision-making and improving care consistency.
Care Pathways logo
Orion Health

Care Pathways

Company Info
Founded: 1993
Headcount: 501-1000
Customers
Verified Customers: 1
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HITRUST R2, HIPAA
Orion Health's Care Pathways is a tool that enables healthcare providers to create, manage, and monitor patient care workflows. It supports the design of both simple and complex care pathways using customizable forms, task management, and pathway-specific permissions. The platform integrates with other Orion Health solutions, providing patient data and task visibility to improve care coordination. It also includes features for auditing, internationalization, and reporting, making it suitable for managing chronic and multidisciplinary care.
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Cary Health

Cary Health Clair

Company Info
Founded: 2017
Headcount: 11-50
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
Cary Health's Clair is an AI-powered clinical reference tool designed to provide clinicians with fast, accurate answers based on the latest medical guidelines and studies. It integrates with EHR systems and customizes workflows to deliver expert-curated, evidence-based information in under a minute. Clair focuses on improving clinical efficiency by optimizing search time and ensuring data accuracy, with curated responses drawn from trusted medical sources like the FDA and NIH.
Company Info
Founded: 1880
Headcount: 5001-10000
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Elsevier ClinicalKey AI, developed with OpenEvidence, provides clinical decision support and clinical reference by integrating generative AI with Elsevier’s medical content and PubMed data. The platform allows clinicians to query in natural language, returning concise, evidence-based summaries with links to primary sources, tailored to patient-specific contexts such as comorbidities. ClinicalKey AI emphasizes responsible AI by aligning with privacy standards and using a transparent approach to ensure reliability in clinical environments.
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Corti

Corti

Company Info
Founded: 2016
Headcount: 51-200
Customers
Verified Customers: 14
Customers Served: Ambulatory Practice, Digital Health Provider, Hospital / Health System
Product Overview
Security and Compliance Certifications: SOC 2 Type 2, UK Cyber Essentials, HIPAA, GDPR
Corti offers an AI-powered platform designed to assist healthcare providers with speech-to-text transcription, live note-taking, documentation, coding, and contextual search. The platform provides real-time transcription for consultations, captures essential clinical details, and automates medical documentation such as referral letters and notes. Corti also supports automated diagnosis and procedure coding to enhance billing accuracy, and its contextual search allows access to internal and external knowledge sources directly within clinical workflows.
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Curbside Health

Curbside Health

Company Info
Founded: 2018
Headcount: 11-50
Customers
Verified Customers: 1
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: SOC 2 Type 1, HIPAA
Curbside Health is a platform designed to create, manage, and analyze clinical practice guidelines and pathways. It allows healthcare organizations to build customizable guidelines using a drag-and-drop interface and collaborate in real-time. The platform offers project management tools, version control, and analytics to monitor clinical decision-making and outcomes. Additionally, it supports testing and EHR integration to enhance implementation and feedback.
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EBSCO

Dyna AI

Company Info
Founded: 1984
Headcount: 1001-5000
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: SOC 2 Type 2, HIPAA
Dyna AI by EBSCO is a clinical decision support tool that leverages AI to provide healthcare professionals with fast, evidence-based answers to natural language queries. It integrates with EBSCO’s DynaMedex and Dynamic Health databases, offering expert-validated information for use at the point of care. The system is designed to assist clinical judgment, not replace it, and adheres to principles like transparency, security, and equity. It is shaped by a multidisciplinary team of clinicians and experts in AI.
Company Info
Founded: 1984
Headcount: 1001-5000
Customers
Customers Served: Hospital / Health System, Ambulatory Practice
Product Overview
Security and Compliance Certifications: SOC 2 Type 2, ISO 27001
EBSCO DynaMed is a clinical decision support tool designed to provide healthcare professionals with evidence-based medical information at the point of care. It features daily updates of clinical content, a robust search function for quick access to medical information, and a system of targeted synopses and recommendations to facilitate fast decision-making. DynaMed integrates with EHR and offers a mobile app for on-the-go access. It also includes features for CME and MOC credits.
Company Info
Founded: 1880
Headcount: 5001-10000
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
Elsevier ClinicalPath is a clinical decision support solution designed to provide evidence-based oncology pathways for clinicians. The platform integrates with EHR systems to deliver real-time, personalized recommendations at the point of care. ClinicalPath helps standardize oncology treatments by providing clear, updated pathways that are customizable based on individual patient needs, aiming to improve outcomes, reduce variability in care, and optimize resource utilization.
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NantHealth

Eviti Advisor

Company Info
Founded: 2007
Headcount: 201-500
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
Eviti Advisor by NantHealth is an oncology decision support platform that provides evidence-based treatment options for cancer care. It is integrated with existing EHR systems to deliver real-time, evidence-backed treatment recommendations at the point of care. Eviti Advisor offers an extensive library of oncology treatment protocols, ensuring alignment with the latest clinical guidelines. It helps clinicians identify the most appropriate treatment options based on individual patient data, supporting personalized care plans while reducing variability and improving treatment outcomes. Additionally, the platform streamlines prior authorization processes by ensuring that recommended therapies meet payer coverage criteria.
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Flatiron Health

Flatiron Assist

Company Info
Founded: 2012
Headcount: 1001-5000
Customers
Verified Customers: 1
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HITRUST CSF, HIPAA
Flatiron Assist is a clinical decision support platform designed for oncology, integrated into the EHR. It provides clinicians with evidence-based treatment pathways, primarily using the NCCN Guidelines for oncology care, while also allowing for customization to meet specific clinical or payer preferences. The platform helps with prior authorization, tracks treatment compliance, and surfaces relevant clinical trials. It supports oncologists in making informed, data-driven decisions at the point of care.
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Glass Health

Glass Health

Company Info
Founded: 2021
Headcount: 1-10
Customers
Customers Served: Digital Health Provider, Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
Glass Health helps healthcare providers develop differential diagnoses and draft clinical plans by analyzing patient summaries and suggesting evidence-based diagnostic and treatment steps. The platform leverages a large language model combined with peer-reviewed clinical guidelines to enhance diagnostic accuracy and improve patient outcomes.
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Kahun

Kahun

Company Info
Founded: 2018
Headcount: 11-50
Customers
Verified Customers: 2
Customers Served: Digital Health Provider, Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA, GDPR
Kahun offers an AI-based clinical reasoning tool that aids healthcare providers in patient intake, assessment, and care planning. The platform leverages a proprietary knowledge graph that incorporates over 30 million evidence-based medical insights, enabling it to generate tailored clinical assessments and decision support at scale. The system is designed with explainability in mind, ensuring that all AI-driven insights are transparent and backed by medical literature.
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MedPearl

MedPearl

Company Info
Founded: 2023
Headcount: 11-50
Customers
Verified Customers: 5
Customers Served: Hospital / Health System, Ambulatory Practice
Product Overview
Security and Compliance Certifications: HIPAA
MedPearl is a clinical decision support tool designed for point-of-care use by clinicians. It integrates patient EHR data with evidence-based medical knowledge, allowing quick access to information relevant to each patient encounter. The platform covers over 550 topics, optimized for rapid reading during consultations, and supports personalized patient communication through shareable content like QR codes. MedPearl aims to enhance diagnostic accuracy and treatment decisions by providing AI-powered, real-time contextualized content.
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Medwise AI

Medwise AI

Company Info
Founded: 2019
Headcount: 1-10
Customers
Customers Served: Digital Health Provider, Ambulatory Practice, Hospital / Health System
Product Overview
Medwise AI offers an AI-powered platform that helps clinicians quickly find accurate answers to clinical questions using a vast database of medical knowledge. It is designed to support evidence-based decision-making in healthcare by providing instant access to relevant clinical guidelines, studies, and expert recommendations. The platform is useful for healthcare providers who need to make informed decisions quickly in a clinical setting.
Company Info
Founded: 2022
Headcount: 1001-5000
Customers
Customers Served: Hospital / Health System, Ambulatory Practice
Product Overview
Merative Micromedex is a comprehensive clinical decision support system that provides healthcare professionals with evidence-based information to enhance patient care. It offers detailed drug reference monographs, including dosing guidelines, FDA-approved and off-label uses, and safety information. The platform includes tools for checking drug interactions, assessing IV compatibility, identifying medications, and comparing drugs. Micromedex also features resources for managing toxicology cases, supporting neonatal and pediatric care, and delivering patient education materials.
OncologyCare logo
EvidenceCare

OncologyCare

Company Info
Founded: 2016
Headcount: 11-50
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HITRUST R2, HIPAA
EvidenceCare's OncologyCare integrates evidence-based oncology pathways directly into the clinician's workflow in the EHR. It provides oncologists with real-time, guideline-driven recommendations, ensuring that treatment decisions are informed by the latest clinical data.
OpenEvidence logo
OpenEvidence

OpenEvidence

Company Info
Founded: 2021
Headcount: 11-50
Customers
Verified Customers: 7
Customers Served: Digital Health Provider, Ambulatory Practice, Hospital / Health System
Product Overview
OpenEvidence offers a clinical trial data management platform designed to streamline the collection, analysis, and reporting of clinical trial data. The platform integrates data from various sources, providing tools for managing patient information, monitoring trial progress, and ensuring regulatory compliance. It is particularly suited for organizations conducting complex, multi-site clinical trials, helping them improve data quality and operational efficiency.
Company Info
Founded: 2020
Headcount: 11-50
Customers
Verified Customers: 5
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Pathway Medical offers a clinical decision support platform designed to help healthcare professionals make rapid, evidence-based decisions at the point of care. The platform utilizes natural language processing and machine learning to process and summarize medical information, offering guideline summaries, interactive algorithms, clinical calculators, and summaries of landmark trials. The platform is accessible via a mobile app that also supports offline usage.
Rejoy Health logo
Rejoy Health

Rejoy Health

Company Info
Founded: 2021
Headcount: 1-10
Customers
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Rejoy Health has developed a chat-based application with their proprietary large language models for processing medical research and clinical data, offering up-to-date, reliable information for healthcare professionals. The system supports doctors in quickly answering complex medical queries, such as drug-related risks, potentially reducing research time from 30 minutes to 30 seconds.
RhythmX

RhythmX

Company Info
Founded: 2023
Headcount: 51-200
Product Overview
RhythmX AI offers a precision care platform that integrates predictive and generative AI to assist physicians in delivering personalized patient care. The platform provides advanced patient risk stratification, surfaces relevant data at the point of care, and offers AI-driven recommendations for interventions such as lab tests, imaging, social care, follow-ups, and medications. By integrating these capabilities into clinical workflows, RhythmX AI aims to enhance physician productivity and improve patient outcomes.
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Zynx Health

ZynxCare

Company Info
Founded: 1996
Headcount: 51-200
Customers
Verified Customers: 12
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
ZynxCare by Zynx Health is an evidence-based clinical decision support solution designed to aid nursing and interdisciplinary teams in improving patient outcomes, reducing clinical variation, and maximizing financial performance. It features a comprehensive library of care plans with actionable interventions aligned with best practice recommendations.
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Zynx Health

ZynxOrder

Company Info
Founded: 1996
Headcount: 51-200
Customers
Verified Customers: 11
Customers Served: Ambulatory Practice, Hospital / Health System
Product Overview
Security and Compliance Certifications: HIPAA
ZynxOrder is a clinical decision support tool designed to help healthcare providers implement and customize evidence-based order sets within their EHR systems.