Mirth Connect is an open-source integration engine that facilitates exchange of healthcare data between disparate formats, supporting standards like HL7, DICOM, and XML.

Health Gorilla's HIE facilitates data exchange via web app and API, and ensures compliance with both national and state regulations, including CalHHS DxF and TEFCA. It includes features a processing engine to enrich and normalize data, a national Master Patient Index, and Record Locator Service to ensure data is attributed to the correct patient. The platform supports the exchange of complete data with national and state networks, aiding in enriching current patient data and supporting public health initiatives.

Innovaccer offers a health data platform that centralizes healthcare data and analytics, focusing on patient-centric care. It offers a range of pre-packaged, customizable solutions called Accelerators, as well as applications for improving clinical and financial outcomes. It also provides developer tools for building on the platform.